UPLC study of inter-component interaction in the system «naproxen - pheniramine maleate»

Authors

  • Natalia O. Eltsova Assistant of the Department of General and Bioorganic Chemistry, Kursk State Medical University, Kursk, e-mail: eltsova-n@mail.ru
  • Elena V. Budko Doctor of Pharmaceutical Sciences, Ph.D., Professor, Head of the Department of General and Bioorganic Chemistry, Kursk State Medical University, Kursk, e-mail: budko.e@list.ru
  • Leonid M. Yampolskii Ph.D. in chemistry, Associate Professor, Department of General and Bioorganic Chemistry, Kursk State Medical University, Kursk, email: yampolsky.leonid@yandex.ru
  • Alexander L. Kulikov leading chemist of the new technologies department, JSC «Pharmstandardleksredstva», Kursk, e-mail: alex-3031@yandex.ru

Keywords:

naproxen, pheniramine maleate, UPLC, stress factors, destruction.

Abstract

The analysis was performed for the two-component system «naproxen - pheniramine maleate» using the method UPLC. It is concluded that strengthening the destructive processes in the presence of pheniramine maleate with naproxen based on the chromatogram initial substances at influence of stress factors and identified degradation products.

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Published

2019-11-18

Issue

Vol. 16 No. 5 (2016): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

UPLC study of inter-component interaction in the system «naproxen - pheniramine maleate». (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 16(5). https://journals.vsu.ru/sorpchrom/article/view/1402

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