Description of eluting capacity of multicomponent mobile phase in HPLC by generalizing parameter

Abstract

A method of dynamic map of chromatographic system, that is developed for ion chromatography
optimization [2,3], is based on the description of eluting capacity of multicomponent mobile phase by a
single generalizing parameter — eluent or eluting strength. According to this method each component of
a mixture under separation can be graphically represented as a band characterizing its equilibrium and
kinetic behavior. In this paper in frame of the earlier suggested retention model for high performance
liquid chromatography (HPLC) [6], a possibility to extend the result, obtained for eluting strength of
multicomponent mobile phase in ion chromatography, is considered