Improvement of extraction instrumental techniques determination of paracetamol by HPLC, TLC, photocolorimetry and digital colorimetry

Authors

  • Lyudmila V. Rudakova РhD., assistant professor of the chair of pharmaceutical chemistry and clinical pharmacy of Voronezh state medical academy, Voronezh
  • Elena Yu. Rossiknina the listener of preliminary courses of Voronezh state medical academy, Voronezh
  • Oleg B. Rudakov Dr Sc. Chem., professor Head of physics and chemistry department of the Voronezh State University of Architecture and Civil Engineering, Voronezh
  • Еlena A. Khorokhordina PhD, assistant professor of the chair of physics and chemistry of the Voronezh State University of Architecture and Civil Engineering Voronezh
  • Hai Dang Сhan the post-graduate student of physics and chemistry department of the Voronezh State University of Architecture and Civil Engineering, Voronezh

Keywords:

paracetamol, acetonitrile, liquid-liquid extraction, HPLC, TLC, photocolorimetry, digital colorimetry.

Abstract

The conditions of paracetamol determination in water solutions by HPLC, TLC,
photocolorimetry and digital colorimetry are proposed. The method of the sample preparation for
paracetamol determining is developed. This method consists of liquid-liquid extraction of paracetamol
from waters solutions of acetonitrile and followed reextraction by salting. A hybrid method of
paracetamol determining combining of TLC and digital colorimeter is considered.

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Published

2019-11-21

Issue

Vol. 13 No. 4 (2013): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

Improvement of extraction instrumental techniques determination of paracetamol by HPLC, TLC, photocolorimetry and digital colorimetry. (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 13(4). https://journals.vsu.ru/sorpchrom/article/view/1668

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