The unlabeled affine sensor for detection of okadaic acid in marine products

Authors

  • Nadezhda A. Karaseva Postgraduate student of Chemistry Department, Lipetsk State Technical University, Lipetsk, е-mail: karaseva_nadia@mail.ru
  • Olga V. Voronezhtseva Candidate of chemistry science of Chemistry Department, Lipetsk State Technical University, Lipetsk
  • Ekaterine Yu. Scherbakova Candidate of engineering sciences, general director of LLC “FEKS”, Moscow
  • Tatyana N. Ermolaeva Doctor of chemistry science, professor of Chemistry Department, Lipetsk State Technical University, Lipetsk

Keywords:

piezoelectric sensor, affine complex, the kinetic constants of formation and dissociation, the constant of affinity, monoclonal antibodies, okadaic acid, analysis of marine products.

Abstract

The affine reaction between antibodies to okadaic acid, immobilized on the sensor’s surface, and
toxin in solution was investigated. The constant of affinity, the kinetic constants of formation and
dissociation were calculated. The unlabeled affine sensor for detection of trace concentration of okadaic
acid was developed. The calibration curve is linear in the range of concentrations 5–500 ng·ml-1, the limit
of detection is 1,4 ng·ml-1. The time of analysis does not exceed 20-30 min

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Published

2019-11-25

Issue

Vol. 12 No. 6 (2012): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

The unlabeled affine sensor for detection of okadaic acid in marine products. (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 12(6). https://journals.vsu.ru/sorpchrom/article/view/1878

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