Chromatographic separation and mass spectrometric investigation of peptides great wax moth

Authors

  • Peter P. Purygin department chairman, department of organic chemistry SSU, professor, (phone member 8 (846) 3345459), Samara state university of Chemistry
  • Olesya S. Sribnaya postgraduate student, Samara state university, elektromodel@mail.ru
  • Natalia A. Klenow candidate of biological sciences Department of Biochemistry, Professor, Samara State University
  • Elena G. Litvinova candidate of biological science, Laboratory of metabolic biochemistry, Institute of Theoretical and Experimental Biophysics,
  • Sergey A. Paramonov postgraduate student Institute of physical chemistry and electrochemistry named after Frumkin Russian Academy of Science
  • Alexey K. Buryak Doctor of Chemistry, department chairman, department of physicalchemical bases of chromatography and chromatomass- spectrometry Institute of physical chemistry Russian Academy of Science, Institute of physical chemistry and electrochemistry named after Frumkin Russian Academy of Science
  • Marina V. Serebryakova candidate of chemical sciences, Laboratory of Proteomic Analysis, Institute of Physical and Chemical Medicine RAMS

Keywords:

Galleria mellonella, MALDI TOF peptides, immunity of insects.

Abstract

We studied the change in peptide composition of haemolymph Galleria mellonella, induced
immunization microorganisms, methods of liquid chromatography and mass spectrometry. Established
that as a result of the immune response there is a lot of new peptide components that were not previously
described for this organism. In the hemolymph of caterpillars were identified as known antimicrobial
peptides. In the antibacterial activity of the fractions studied hemolymph detected unstudied peptides of
interest for studies aimed at studying the immune response and innate immunity in insects.

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Published

2019-11-25

Issue

Vol. 11 No. 1 (2011): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

Chromatographic separation and mass spectrometric investigation of peptides great wax moth. (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 11(1). https://journals.vsu.ru/sorpchrom/article/view/1897

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