Analytical signal amplification of quarts crystal immunosensor for determining sulfamethazine with gold nanoparticles

Authors

  • Elena V. Melihova PhD, Chemistry Department, Lipetsk State Technical University, Lipetsk
  • Olga Yu. Shashkanova Post-graduat Chemistry Department, Lipetsk State Technical University, Lipetsk
  • Tatyana N. Ermolaeva doctor of science, professor of chemistry, Lipetsk State Technical University, Lipetsk, e–mail: ermolaeva@stu.lipetsk.ru

Keywords:

immunosensor, Sulfamethazine.

Abstract

Heterogenetic reaction of Sulfamethazine – antibody, proceeding on an electrode surface of
quarts crystal piezosensor for flow injection definition of Sulfamethazine is studied. Possibility of
strengthening of an analytical immunosensor signal (Δf) with the help gold nanoparticle of various
diameter is considered. Shown, that use of particles, diameter 5 nanometers, leads to increase in an
analytical signal more than in 4 times, to decrease in a limit of detection of Sulfamethazine with 1,9 to 0,6
mkg/ml. The immunosensor is approved at definition of Sulfamethazine in foods

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Published

2019-11-26

Issue

Vol. 11 No. 2 (2011): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

Analytical signal amplification of quarts crystal immunosensor for determining sulfamethazine with gold nanoparticles. (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 11(2). https://journals.vsu.ru/sorpchrom/article/view/1924

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