Chromatographic isolation and purification of low-molecular-weight peptide complexes from sea-urchin eggs

Abstract

Cross-flow microfiltration, solid phase extraction, reversed-phase high performance liquid
chromatography and high performance were used for separation and purification of low molecular weight
peptides from the sea urchins eggs Strongylocentrotus pallidus and Strongylocentrotus droebachiensis. It
was shown that the isolated peptides have pronounced stimulating activity with respect to tissues of
mesodermal origin (spleen, heart, liver).