Eqilibrium and kinetics of uric acid sorbtion by molecular imprinted polymer sorbent

Authors

  • Anastasia P. Leschinskaya junior research worker, Institute of Macromolecular Compounds, Russian Academy of Sciences
  • Irina V. Polyakova senior research worker, Institute of Macromolecular Compounds, Russian Academy of Sciences, e-mail: pol_irina_val@list.ru
  • Anna R. Groshikova research worker, Institute of Macromolecular Compounds, Russian Academy of Sciences
  • Oleg A. Pisarev laboratory chief, Institute of Macromolecular Compounds, Russian Academy of Sciences
  • Eugenie F. Panarin institute director, Institute of Macromolecular Compounds, Russian Academy of Sciences

Keywords:

uric acid, molecularly imprinted polymer, plasmasorption, hyperuricemia, gout.

Abstract

To elaborate the efferent methods of eliminating the uric acid (UA) directly from human
organisms, the UA-MIP-16 was synthesized. The authors have realized study of the specific and nonspecific
sorption of the UA by UA-MIP-16. The equilibrium adsorption of uric acid and its closest
structural analogue xantine from the model aqua solutions was investigated. The main thermodynamic
functions of uric acid and xantine adsorption on UA-MIP-16 and on the NIP (non-imprinted polymeric
sorbent) demonstrated the prevalence of specific binding uric acid with imprinted sorbent. Kinetic and
parameters of sorption uric acid by UA-MIP-16 from model aqua solutions and peritoneal liquid was
studying.

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Published

2019-11-26

Issue

Vol. 11 No. 5 (2011): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

Eqilibrium and kinetics of uric acid sorbtion by molecular imprinted polymer sorbent. (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 11(5). https://journals.vsu.ru/sorpchrom/article/view/1985

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