Nanodiamond-included cellulose matrix composite for chromatographic purification of proteins

Abstract

Synthesis of composite sorbent which matrix includes nanodiamonds is an actual task for
purification of proteins. For this purpose the series of composite sorbents were synthesized. Granules of
high-permeability cellulose are matrix of these sorbents. With the change of synthesis conditions, such as:
pH, ratio between diacetate cellulose – nanodiamonds we can obtain sorbents with various kinetic and
ion-exchange capacity characteristics. At the same time it is possible to determine synthesis conditions to
change non-equilibrium regime of sorption to quasi-equilibrium one