Methods for characterisation of reversed-phase chromatographic packings (review)

Authors

  • Grigoriy B. Golubitckiy doctor of sciences (chеmistry), the head of new technologies departament of JSC “Pharmstandard-Leksredstva”, Kursk, e-mail: iirogirg@narod.ru

Keywords:

reversed-phase packings, endcapping, hydrophobicity, residual silanol activity, shape selectivity, hydrophilic-hydrophobic balance, chemometric treatment of data.

Abstract

Test procedures for reversed-phase high-performance liquid chromatographic packings,
published in 1990 – 2012, are reviewed. Some works, concerning the most important problems of this
issue, correspond to more recent period. In this review the physical and chemical, chromatographic
methods of investigation and approaches to stability evaluation are presented. There is no a universal test
for reversed phases evaluation and each method has his own peculiarities and field of application. This
area has great scientific and practical importance and one should expect its development in future.

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Published

2019-11-21

Issue

Vol. 13 No. 4 (2013): Sorbtsionnye i Khromatograficheskie Protsessy

Section

Статьи

How to Cite

Methods for characterisation of reversed-phase chromatographic packings (review). (2019). Sorbtsionnye I Khromatograficheskie Protsessy, 13(4). https://journals.vsu.ru/sorpchrom/article/view/1657

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