Nanodiamond-included cellulose matrix composite for chromatographic purification of proteins

  • Arina A. Sevostyanova engineer, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg
  • Alexander A. Demin Doctor of Science, Head of the Laboratory, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg, demin@imc.macro.ru
  • Alexander T. Melenevsky research associate, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg, melenev@imc.macro.ru
  • Ekaterina N. Pavlova research associate, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg
  • Elena S. Nikiforova research associate, nstitution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg
Keywords: impregnation, nanomaterials, cellulose, chromatography.

Abstract

Synthesis of composite sorbent which matrix includes nanodiamonds is an actual task for
purification of proteins. For this purpose the series of composite sorbents were synthesized. Granules of
high-permeability cellulose are matrix of these sorbents. With the change of synthesis conditions, such as:
pH, ratio between diacetate cellulose – nanodiamonds we can obtain sorbents with various kinetic and
ion-exchange capacity characteristics. At the same time it is possible to determine synthesis conditions to
change non-equilibrium regime of sorption to quasi-equilibrium one

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Published
2019-11-26
How to Cite
Sevostyanova, A. A., Demin, A. A., Melenevsky, A. T., Pavlova, E. N., & Nikiforova, E. S. (2019). Nanodiamond-included cellulose matrix composite for chromatographic purification of proteins. Sorbtsionnye I Khromatograficheskie Protsessy, 11(6). Retrieved from https://journals.vsu.ru/sorpchrom/article/view/1988