A potentiometric multisensory system based on MF-4SC membranes containing silica with a functionalized surface for the determination of sulphanilamide and potassium ions

  • Anastasia S. Yelnikova Voronezh State University, Voronezh, Russian Federation
  • Tatyana S. Kolganova Voronezh State University, Voronezh, Russian Federation
  • Anna V. Parshina Voronezh State University, Voronezh, Russian Federation
  • Olga V. Bobreshova Voronezh State University, Voronezh, Russian Federation
DOI: https://doi.org/10.17308/sorpchrom.2020.20/3054
Keywords: DP-sensors,, multisensory systems,, perfluorosulphonic acid membranes,, silica,, functionalisation of the dopant surface,, hybrid materials,, sulphanilamide

Abstract

Sulphanilamide preparations are widely used in medicine and veterinary medicine. HPLC, capillary electropho-resis, spectrophotometry, and titrimetry are used for the control of the content of residual amounts of sulphanilamides in food, drinking water, environmental objects, and the analysis of pharmaceuticals. In the same time, the number of sensors for their determination is limited. The aim of the study was the development of potentiometric multisensory system with DP-sensors (DP – Donnan potential) for the determination of anions and zwitter ions of sulphanilamide together with potassium cations in aqueous solutions in a wide pH range. The materials of DP-sensors were perfluoromembranes MF-4SC, containing silica nanoparticles with a surface modified with 3-aminopropyl and 3-(2-imidazolin-1-yl) propyl groups. The sensitivity of DP-sensors based on the studied membranes to zwitter ions and sulphanilamide anions was significant in the concentration range from 1.0∙10-4 to 1.0∙10-2 M. This was due to the protonation of sulphanilamide ani-ons in the membrane caused by the difference in pH of the external and internal solutions. In this case, the presence in the structure of the analyte of a positively charged aromatic amino group and a negatively charged sulphanilamide group ensured the interaction with membrane sulphogroups and amino groups on the dopant surface, respectively. For the or-ganization of the multisensory system, the MF-4SC + 3 wt.% SiO2 (10 mol.% R1) membrane with the highest sensitivity to sulphonamide ions and MF-4SC + 3 wt.% SiO2 membrane were chosen. These membranes paired up provide the smallest correlation between the responses of sensors in the system. The relative error and relative standard deviation of the determination of sulphanilamide ions were 3-9 and 8-16%, potassium ions - 0.4-14 and 3-14%, respectively. Benefits of the developed multisensory system for the determination of sulphanilamide in aqueous solutions in comparison with nitrite titration methodology recommended by the State Pharmacopoeia are rapidity, no need for pH correction and the use of other reagents, as well as the possibility of simultaneous determination of sulphanilamide with alkali metal ions, which are components of pharmaceutical and technological media.

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Author Biographies

Anastasia S. Yelnikova, Voronezh State University, Voronezh, Russian Federation

2-nd year master’s stu-dent, Department of Analytical Chemistry, Voro-nezh State University, Voronezh

Tatyana S. Kolganova, Voronezh State University, Voronezh, Russian Federation

PhD in Chemistry, lecturer, Department of Analytical Chemistry, Voronezh State University, Voronezh

Anna V. Parshina, Voronezh State University, Voronezh, Russian Federation

Doctor of Chemical Scienc-es, Associate Professor, Department of Analytical Chemistry, Voronezh State University, Voronezh parshina_ann@mail.ru

Olga V. Bobreshova, Voronezh State University, Voronezh, Russian Federation

Doctor of Chemical Sciences, professor, chief researcher, Department of Analytical Chemistry, Voronezh State University, Voronezh

References

Dmitrienko S.G., Kochuk E.V., Tolma-cheva V.V., Apyari V.V. et al., Food chemistry, 2015, Vol. 188, pp. 51-56. DOI: 10.1016/j.foodchem.2015.04.123.

He B., Chen W., J. Braz. Chem. Soc., 2016, Vol. 27, No 12, pp. 2216-2225. DOI: 10.5935/0103-5053.20160114.

Peixoto P.S., Tóth I.V., Segundo M.A., Lima J.L.F.C., Int. J. Environ. Anal. Chem., 2016, Vol. 96, No 2, pp. 185-202. DOI: 10.1080/03067319.2015.1128539.

GOST R 54904-2012. Food products, food raw materials. Method for determination of sulfonamides, nitroimidazoles, penicillins, am-phenicols by high performance liquid chroma-tography - mass spectrometry, M., Standartin-form, 2013, 23 p.

FS.2.1.0038.15 Sulfanilamid. Available at: http://pharmacopoeia.ru/fs-2-1-0038-15-sulfanilamid/ (accessed 14 October 2020).

Maggira M., Deliyanni E.A., Samanidou V.F., Molecules, 2019, Vol. 24, No 11, P. 2086. DOI: 10.3390/molecules24112086.

Amelin V.G., Volkova N.M., Timofeev A.A., Tretyakov A.V., J. of Anal. Chem., 2015, Vol. 70, No 9, pp. 1076-1084. DOI: 10.7868/S0044450215090029.

Li Z., Li Y., Qi M., Zhong S. et al., J. Sep. Sci., 2016, Vol. 39, No 19, pp. 3818-3826. DOI: 10.1002/jssc.201600308.

Ji H., Wu Y., Duan Z., Yang F. et al., Electrophoresis, 2017, Vol. 38, No 3-4, pp. 452-459. DOI: 10.1002/elps.201600364.

Errayess S.A., Lahcen A.A., Idrissi L., Marcoaldi C et al., Spectrochim. Acta A Mol. Biomol. Spectrosc, 2017, Vol. 181, pp. 276-285. DOI: 10.1016/j.saa.2017.03.061.

Zamora-Gálvez A., Ait-Lahcen A., Mercante L.A., Morales-Narváez E. et al., Anal.

Chem., 2016, Vol. 88, No 7, pp. 3578-3584. DOI: 10.1021/acs.analchem.5b04092.

He B., Yan S., Int. J. Electrochem. Sci., 2017, Vol. 12, pp. 3001-3011. DOI: 10.20964/2017.04.56.

Yadav S.K., Choubey P.K., Agrawal B., Goyal R.N., Talanta, 2014, Vol. 118, pp. 96-103. DOI: 10.1016/j.talanta.2013.09.061.

Kamel A.H., Almeida S.A., Sales M.G.F., Moreira F.T., Anal Sci., 2009, Vol. 25, No 3, pp. 365. DOI: 10.2116/analsci.25.365.

Soleymanpour A., Rezvani S.A., Mater. Sci. Eng. C, 2016, Vol. 58, pp. 504. DOI: 10.1016/j.msec.2015.08.034.

Kharitonov S.V., Gorelov I.P., Pharm. Chem. J., 2000, Vol. 34, No 12, pp. 673.

Bourais I., Maliki S., Mohammadi H., Amine A., Enzyme Microb. Technol., 2017, Vol. 96, pp. 23-29. DOI: 10.1016/j.enzmictec.2016.09.007.

Safronova E., Parshina A., Kоlganova T., Bobreshova O. et al., J. Electroanal. Chem., 2018, Vol. 816, pp. 21-29. DOI: 10.1016/J.JELECHEM.2018.03.028.

Parshina A.V., Titova T.S., Evdokimova D.D., Bobreshova O.V. et al., Membranes and Mem-brane Technologies, 2019, Vol. 1, No 4, pp. 220-228. DOI: 10.1134/S2517751619040073.

Chienthavorn O., Smith R.M., Chroma-tographia, 1999, Vol. 50, No 7-8, pp. 485-489. DOI: 10.1007/BF02490746.

Mikheev A.G., Safronova E.Y., Yaro-slavtsev A.B., Pet. Chem., 2013, Vol. 53, No 7, pp. 504-510. DOI: 10.1134/ S0965544113070104.

Sarapulova V.V., Klevtsova A.V., Pismenskaya N.D., Membranes and Membrane Technologies, 2020, Vol. 2, No 4, pp. 272-282. DOI: 10.1134/S2517751620040101.

Published
2020-11-25
How to Cite
Yelnikova, A. S., Kolganova, T. S., Parshina, A. V., & Bobreshova, O. V. (2020). A potentiometric multisensory system based on MF-4SC membranes containing silica with a functionalized surface for the determination of sulphanilamide and potassium ions. Sorbtsionnye I Khromatograficheskie Protsessy, 20(5), 615-623. https://doi.org/10.17308/sorpchrom.2020.20/3054
Issue
Vol 20 No 5 (2020): Sorbtsionnye i Khromatograficheskie Protsessy
Section
Статьи