Gas chromatography-mass spectrometry method for the determination of free bisphenol A in ethanol extracts
Abstract
The article presents an express method for the determination of bisphenol A in ethanol extracts using gas chromatography-mass spectrometry (GC-MS). The development is aimed at solving the problem of improving the analytical quality control and safety of food containers made of plastics or having an epoxy coating. The GC-MS method has acquired the status of a reference method in accredited analytical laboratories for the identification of contaminant impurities in food and alcohol products. Bisphenol A (BPA) is used as a monomer in a number of plastics and epoxy resins. Free BPA may be contained in quantities exceeding the permissible level in food packaging. Despite the relatively low toxicity of BPA, it can accumulate in the human body and cause harmful effects on its health. The development of express methods for the identification and quantification of BPA on chromatography-mass-spectrometric equipment is a relevant task. Research was performed using Agilent 8890 gas chromatograph equipped with a mass selective detector 5977B , an Ultra ALLOY capillary column®-5 UA5-30M-0.25F, with the length of 30 m. As a result of the experiments, the optimal modes for the determination of bisphenol A in ethanol extracts were selected. The developed method for the determination of BPA in ethyl solutions using GC-MS can be recommended for control of the quality and safety of food containers, control of BPA in alcohol-containing liquids, as well as for forensic medical examination as a reference method for confirmation of the reliability of BPA identification.
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