The use of chromatographic methods for the determination of 3-(trifluoromethyl )-aniline in biological material
Keywords:
derivatives of 3-(trifluoromethyl)-aniline, TLC, column chromatography, HPLS, chemical-toxicological investigation.
Abstract
Peculiarities of chromatographic behaviour of the derivatives of 3-(trifluoromethyl)-aniline in thin layers and columns of hydroxylated sorbents depending on the polarity of the mobile phases have been studied. Parameters, characterizing the conditions of defining the investigated substances using the TLC methods, column chromatography of low pressure and high pressure liquid chromatography (HPLS) have been determined. Methods for chemico-toxicological investigation of the derivatives of 3-(trifluoromethyl)aniline with application of chromatographic analysis methods have been developed.
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References
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2.Generali J.A., Cada D.J., Hospitalpharmacy, 2014, Vol. 49, No 6, рр. 517-520. Lazaros G. et al, Annals of gastroenterology, 2001, Vol. 14, No 2, pp. 125-127.
3.Hung H.C., Lin I.H., Shiue K.F., Huang B.C., Journal Intern. Med. Taiwan, 2007, Vol.18, pp. 35-39.
4.Bakdash A. еt al., Toxichem+Krimtech, 2006, Vol. 73, No 2, pp. 61-65.
5.Matsuzaki Y., Nagai D., Ichimura E., Journal of Gastroenterology, 2006, Vol. 41, No 3, рр. 231-239.
6.Shormanov V.K., Andreeva Ju.V., Omel'chenko V.A., Sudebno-medicinskaja jekspertiza, 2014, Vol. 57, No 5, рр. 18-20.
Published
2019-11-14
How to Cite
Shormanov, V. K., Andreeva, J. V., Suhomlinov, Y. A., & Omelchenko, V. A. (2019). The use of chromatographic methods for the determination of 3-(trifluoromethyl )-aniline in biological material. Sorbtsionnye I Khromatograficheskie Protsessy, 16(1), 100-109. Retrieved from https://journals.vsu.ru/sorpchrom/article/view/1330
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