Сорбционно-флуориметрическое определение энрофлоксацина с применением наночастиц магнетита, модифицированных моно и дикатионными ПАВ

Sergei N. Shtykov; Olga R. Egunova; Irina S Reshetnikova; Alla B. Mirgorodskaya; Lucia Ya. Zakharova

Sergei N. Shtykov Dr. Sci. (Chemistry), Professor, Division of Analytical Chemistry and Chemical Ecology, N.G. Chernyshevskii Saratov State University, Saratov, E-mail: shtykovsn@mail.ru
Olga R. Egunova a graduate student of the 3rd year of study, N.G. Chernyshevskii Saratov State University, Saratov, E-mail: egunova.or@gmail.com
Irina S Reshetnikova a graduate student of the 1st year of study, N.G. Chernyshevskii Saratov State University, Saratov, E-mail: Irkasar@ya.ru
Alla B. Mirgorodskaya chem. sci., Senior Researcher, Laboratory of highly organized structures, A.E. Arbuzov Institute of Organic and Physical Chemistry KazSC RAS; e-mail: mirgorod@iopc.ru
Lucia Ya. Zakharova Dr. Sci. (Chemistry), Honoured Scientist of Republic of Tatarstan, Head of the laboratory of Highly Organized Media of the A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Research Center of the Russian Academy of Sciences, Professor, Division of Organic Chemistry, Kazan national research technological university, Kazan, E-mail: lucia@iopc.ru

Keywords: magnetite, nanoparticles, modification, enrofloxacin, sorption, determination, fluorimetry

Abstract

In the current study, superparamagnetic magnetite nanoparticles (MNP) were synthesized and surface-modified with two types of cationic surfactants: conventional monocationic cetyltrimethylammonium bromide (CTAB) and dicationic (gemini) surfactants of the 12-s-12 (s = 2, 4, 6) type to improve the stability of MNP and their adsorption properties with respect to enrofloxacin as a representative of fluoroquinolone antibiotics. The effect of various experimental factors: the pH of solution, the influence of concentration, the contact time and the quantity of the MNP sample were studied by using the batch technique. The characterization of the form, size of MNP, surface modification was performed with transmittance electron microscopy. It was established that the sizes of all MNP modified by cationic surfactants were varied between 8-9 nm and the thickness of organic shell was within 1.2-2.5 nm. It was found that the most high zeta-potential (+43 - +46) of modified MNP was at pH 3 and strongly decreased with increasing the pH value. The optimal sorption time of enrofloxacin was 15 min and in optimal conditions the extent of sorption is 80-90% as from pure water as buffer solution at pH 3 that was proved fluorimetrically by analyzing the enrofloxacin content in solution after MNP preconcentration.

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Sorption-fluorimetric determination of enrofloxacin with magnetite nanoparticles modified by mono and dicationic surfactants

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