Different methods of electrophoretic determination bioactive substances in the form of their complexes with metal ions
Abstract
Possibility of determination of bioactive organic substances in the form of their complexes with
metal ions by the methods of capillary electrophoresis (CE): electroinjection (EIA) and electrophoretic
microanalysis (EMA); capillary zone electrophoresis (CZE) with injection of preliminary prepared
complex and with addition of one participant of complexation to the back ground electrolyte (BGE) –
metal cation or bioactive organic substances (biogenic amines, neurotransmitter amino acids, aromatic
hydroxyacids, cateсhins and others) were investigated.
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соединения металлов в медицине / Киев: Наук. Думка, 1986. 216 с.
2.Эндокринология / под ред. Лавина Н. 1999. 1128 с.
3.Руководство по лабораторной клинической диагностике / под ред. Меньшикова
В.В. М., Медицина. 1982. 576 с.
4.Sorenson J.R.I., Hangarter W. Treatment of rheumatoid and degenerative diseases with
copper complexes: A review with emphasis on copper-salicylate// Inflammation. 1997. V.
2. № 3. P. 217-238.
5.Sorenson J.R.I. Copper chelates as possible active forms of the anti-arthritic agents // J.
Med. Chem. 1976. V. 19. № 1. P. 135-148.
6.Liang X., Sadler P.J. Cyclam complexes and their applications in medicine // Chem.
Soc. Rev. 2004. V. 33. P. 246-266.
7.Руководство по капиллярному электрофорезу / под ред. А.М. Волощука. М. 1996.
112 с.
8.Britz-McKibbin P., Terabe S. On-line preconcentration strategies for trace analysis of
metabolites by capillary electrophoresis// J. Chrom. A. 2003. V. 1000. P. 917-934.
9.Андреев В.П. // Журн. Аналит. Химии. 1999. Т.54. № 7. С.769-776.
10. Andreev V.P., Ilyina N.B., Lebedeva E.V., Kamenev A.G., Popov N.S.
Electroinjection analysis - Concept, mathematical model and applications// J. Chromatogr.
A. 1997. V. 772. № 1. P. 115-127.
11. Harmon B.J., Patterson D.H., Regnier F.E. Electrohoretically mediated
microanalysis of ethanol// J. Chromatogr A. 1993. V 657 № 1. P 429 – 434.
12. Harmon B.J., Patterson D.H., Regnier F.E. Mathematical treatment of
electrophoretically mediated microanalysis// Anal. Chem. 1993. V 65. № 19. P. 2655-2662.
13. Osbourn D.M., Weiss D.J., Lunte C.E. On-line preconcentration methods for
capillary electrophoresis// Electrophoresis. 2000. V. 21. P. 2768-2779
14. Даванков В.А., Навратил Дж., Уолтон Х. Лигандообменная хроматография. /
Пер. с англ. М.: Мир. 1990. 294 с.