Reversed-phase HPLC flumequine and ciprofloxacin in the organised environments
Keywords:
fluoroquinolones, determination, high performance liquid chromatography, organized media.
Abstract
The effect of the surfactant and cyclodextrin nature and concentration on the separation and limit
of detection of flumequine and ciprofloxacin in the mixture with other antibiotics was studied by RP
HPLC with fluorimetric detector. The procedure for ciprofloxacin determination based on the
enhancement effect of γ-cyclodextrin in drugs produced by different manufactures was developed
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References
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and determination of five quinolone antibotics using isocratic reversed-phase HPLC:
Application to stability studies on an ofloxacin tablet formulation // J. Pharm. Biomed.
Anal. 2005. V. 39. № 3-4. P.769-775.
2.Inês M., Santoro R.M., Kassab N. M., Singh A.l K., Kedor-Hackmam E. M.
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin
fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid
chromatography // J. Pharm. Biomed. Anal. 2006. V. 40. №1. P.179-184.
3.Mancean S., Giequel M., Lanrentie M. Simultaneous determination of enrofloxacin and
ciprofloxacin in animal biomedical fluids by high-performance liquid chromatography.
Application in pharmacokinetic studies in pig and rabbit // J. Chromatogr. B: Biomed. Sci.
Appl. 1999. V.726. №1-2. P.175-178.
4.Imre S., Dogaru M.T., Vari C.E., Muntean T., Kelemen L. Validation of an HPLC
method for the determination of ciprofloxacin in human plasma // J. Pharm. Biomed. Anal.
2003. V. 33. №1. P.125-130.
5. Ramos M., Aranda A., Garcia E., Reuvers T., Hooghuis H. Simple and sensitive
determination of five quinolones in food by liquid chromatography with fluorescence
detection // J. Chromatogr. B. 2003. V. 789. №2. P.373-381.
6. Zotou A., Miltiadou N. Sensitive LC determination of ciprofloxacin in
pharmaceutical preparations and biological fluids with fluorescence detection // J. Pharm.
Biomed. Anal. 2002.V. 28. №3-4. P.559-568.
7. Штыков С.Н. Химический анализ в нанореакторах. Основные понятия и
применение // Журн. аналит. химии. 2002. Т.57. №10. С.1018-1028.
8. El-Kemary M., Dauhal A. Photochemistry and photophysics of cyclodeхtrin caged
drugs: relevance to their stability and efficiency // Cyclodeхtrin materials in
photochemictry, photophysics and photobiology. Ed. by Douhal A. - Elsevier. 2006. V.1.
P.79-105
Published
2019-11-27
How to Cite
Smirnova, T. D., Shtykov, S. N., & Nevrueva, N. B. (2019). Reversed-phase HPLC flumequine and ciprofloxacin in the organised environments. Sorbtsionnye I Khromatograficheskie Protsessy, 10(1). Retrieved from https://journals.vsu.ru/sorpchrom/article/view/2032
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