The influence of vitamineral sorbents on the purulent wound process

  • Uliana А. Krut deputy director for project and career guidance, candidate of biology, Belgorod National Research University, Belgorod. ulyana- montus@mail.ru
  • Alexandr I. Vezentsev head of the department of general chemistry of the Institute of pharmacy, Doctor of engineering, professor, chemistry and biology, Belgorod National Research University, Belgorod. vesentzev@bsu.edu.ru
  • Elena V. Kuzuvova student of the Institute of pharmacy, chemistry and biology, faculty of pharmacy, Belgorod National Research University, Belgorod. 1015artek1015@mail.ru
  • Alexandra I. Radchenko student of the Institute of pharmacy, chemistry and biology, faculty of pharmacy, Belgorod National Research University, Belgorod. sandrinkaradchen- ko@gmail.com
  • Galina M. Shaydorova master degree (магистр) of the Institute of pharmacy, chemistry and biology, faculty of pharmacy, Belgorod National Research University, Belgorod. 800761@bsu.edu.ru
Keywords: phytomineral sorbent, septic wounds, hemosorbtion, morphological analysis of the blood of rats.

Abstract

The purpose of this study is to determine the effect of modified montmorillonite clays on the
wound-healing process of purulent wounds of laboratory rats. The results of the study of phyto-mineral sorbents as an antiseptic and stimulating regeneration agent are presented. The effect of modified montmorillonitecontaining clay with an extract of the medicinal plant Thymus serpylum on the healing process of purulentnecrotic lesions of the skin in laboratory Wistar rats was studied. In the course of the research, the wound-healing effect of phyto-mineral adsorbents in the form of powder and gel was studied. Panthenol Pharmstandard was used as a reference drug. The clinical picture of the blood of rats after the application of a model wound was also investigated, and data on platelet, leukocyte, and red blood cell studies are presented. where Panthenol Pharmstandard was used, was the lowest (on average, 65% less than other groups). However, the use of phyto-mineral sorbents in the form of a powder stimulated a more earlier decrease in the area of the wound defect than in other animals. It was also proved that when using phytomineral sorbents in the early stages of the wound process, it contributes to the rapid restoration of connective tissue. Secondary reinfection did not occur, due to the high sorption capacity of drugs.

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Published
2018-12-06
How to Cite
KrutU. А., Vezentsev, A. I., Kuzuvova, E. V., Radchenko, A. I., & Shaydorova, G. M. (2018). The influence of vitamineral sorbents on the purulent wound process. Sorbtsionnye I Khromatograficheskie Protsessy, 18(6), 921-926. https://doi.org/10.17308/sorpchrom.2018.18/621