Physicochemical study of the processes of b-cyclodextrin hydrates dehydration

Lyudmila N. Zelenina; Tatyana V. Rodionova; Tamara P. Chusova; Anastasia V. Sartakova; Andrey Yu. Manakov

doi:10.17308/kcmf.2024.26/12435

Lyudmila N. Zelenina Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation; Novosibirsk State University, 2 Pirogova st., Novosibirsk 630090, Russian Federation https://orcid.org/0000-0002-5027-5278
Tatyana V. Rodionova Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation https://orcid.org/0000-0001-8989-1900
Tamara P. Chusova Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation https://orcid.org/0000-0001-5246-0138
Anastasia V. Sartakova Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation; Novosibirsk State University, 2 Pirogova st., Novosibirsk 630090, Russian Federation
Andrey Yu. Manakov Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation https://orcid.org/0000-0003-0214-8714

DOI: https://doi.org/10.17308/kcmf.2024.26/12435

Keywords: b-cyclodextrin hydrates, PXRD, Static tensimetry, Saturated vapor pressure, Dehydration enthalpy and entropy

Abstract

The research involved synthesizing b-cyclodextrin hydrates of the b-CD·nH₂O (n = 11.9–0.9) composition.

The obtained compounds were studied by powder X-ray diffraction (XRD), which revealed the transition from a monoclinic unit cell to an orthorhombic one with a decrease in the water content in the samples. The pressure of saturated vapor of the water in the b-CD·nH₂O (n = 10.6–7.0) hydrates was measured by static tensimetry with membrane null-manometer over a wide temperature range (293–384 K) under conditions of a quasi-constant hydrate composition. The measured vapor pressure increases in proportion to the increase in the water content of the hydrate samples.

The experimental data reduced to a single composition of b-CD·1H₂O were approximated by the lnp(1/T) equation, from which the thermodynamic parameters (∆prH°T and ∆prS°T) of the process of b-cyclodextrin hydrate dehydration were calculated. This information was used to estimate the binding energies of the water molecules to the b-CD framework

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Author Biographies

Lyudmila N. Zelenina, Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation; Novosibirsk State University, 2 Pirogova st., Novosibirsk 630090, Russian Federation

Cand. Sci. (Chem.), Research Fellow at the Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences; Senior Lecturer, Novosibirsk State University (Novosibirsk, Russian Federation)

Tatyana V. Rodionova, Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation

Cand. Sci. (Chem.), Research Fellow at the Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences (Novosibirsk, Russian Federation)

Tamara P. Chusova, Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation

Cand. Sci. (Chem.), Research Fellow at the Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences (Novosibirsk, Russian Federation)

Anastasia V. Sartakova, Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation; Novosibirsk State University, 2 Pirogova st., Novosibirsk 630090, Russian Federation

5th year student of the Faculty of Natural Sciences, Novosibirsk State University (Novosibirsk, Russian Federation)

Andrey Yu. Manakov, Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences, 3 Lavrent’ev ave., Novosibirs 630090, Russian Federation

Dr. Sci. (Chem.), Chief Researcher at the Nikolaev Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences (Novosibirsk, Russian Federation)

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