Sorption of flavonoids and aromatic acids on hypercrosslinked polystyrene in systems with addition of imidazolium ionic liquids

  • Varvara M. Raznitsyna Samara National Research University, Samara, Russia
  • Roman V. Shafigulin Samara National Research University, Samara, Russia
  • Kirill Yu. Vinogradov Samara National Research University, Samara, Russia
  • Vladimir A. Kurkin FSBEI HE SamSMU MOH Russia, Samara, Russia
  • Andzhela V. Bulanova Samara National Research University, Samara, Russia
Keywords: imidazolium ionic liquids, hypercrosslinked polystyrene, reversed-phase high-performance liquid chroma-tography, flavonoids, aromatic acids

Abstract

In this work the effect of the addition of five imidazolium ionic liquids (ILs) to the water-acetonitrile eluents on the sorption of aromatic acids and flavonoids on hypercrosslinked polystyrene (HPS) was evaluated by reversed-phase HPLC (RP HPLC). It was found that both the nature of the cation and the nature of the anion of the used IL influence the retention of the studied compounds. The retention of aromatic acids and flavonoids in the systems without and with the addition of trifluoroacetic acid (TFA) to the eluent was investigated. It was shown that the addition of TFA to the water-acetonitrile eluent changes the mechanism of action of imidazolium ILs on the retention of sorbates on HPS. In particular, the sequence of elution of ferulic acid, salicylic acid and caffeic acid in the systems with addition of ILs to the mobile phase on HPS varies depending on the pH of the medium (depend of the addition of TFA). The Snyder-Soczewiński and Soczewiński–Wachtmeister models were used to evaluate the influence of water-acetonitrile eluent composition on the retention of studied compounds. The angular coefficients of the corresponding models were calculated.

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Author Biographies

Varvara M. Raznitsyna, Samara National Research University, Samara, Russia

postgraduate student of the Department of Physical Chemistry and Chromatography, Samara University, Russia, e-mail: v_raznitsyna@mail.ru

Roman V. Shafigulin, Samara National Research University, Samara, Russia

Dr.Sci (Chemistry), head of the Department of Physical Chemistry and Chromatography, Samara University, Russia, e-mail: shafiro@mail.ru

Kirill Yu. Vinogradov, Samara National Research University, Samara, Russia

postgraduate student of the Department of Physical Chemistry and Chromatography, Samara University, Russia, e-mail: winyur@yandex.ru

Vladimir A. Kurkin, FSBEI HE SamSMU MOH Russia, Samara, Russia

Dr.Sci (Pharmaceutical Sciences), head of the Department of Pharmacognosy with Botany and Fundamentals of Phytotherapy, FSBEI HE SamSMU MOH Russia, e-mail: kurkinvladimir@yandex.ru

Andzhela V. Bulanova, Samara National Research University, Samara, Russia

д.х.н., профессор кафедры физической химии и хроматографии, Самарский университет, Самара, Россия

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Published
2024-12-08
How to Cite
Raznitsyna, V. M., Shafigulin, R. V., Vinogradov, K. Y., Kurkin, V. A., & Bulanova, A. V. (2024). Sorption of flavonoids and aromatic acids on hypercrosslinked polystyrene in systems with addition of imidazolium ionic liquids. Sorbtsionnye I Khromatograficheskie Protsessy, 24(5), 682-694. https://doi.org/10.17308/sorpchrom.2024.24/12508