Obtaining of characteristic profiles of steroid hormones by high-performance thin-layer chromatography

  • Ekaterina V. Obedkova PhD student of analytical chemistry department of chemical faculty, St. Petersburg state university, St. Petersburg, e-mail:obedkovaev@gmail.com
  • Ludmila A. Kartsova Dr.Sc.Chem. the professor of organic chemistry department of chemical faculty, St. Petersburg state university, St. Petersburg, email:kartsova@gmail.com
  • Dmitrii O. Kirsanov docent of radiochemistry St. Petersburg state university, St. Petersburg
  • Anton A. Golishev five-year student of organic chemistry department of chemical faculty, St. Petersburg state university, St. Petersburg
Keywords: chromatographic patterns, high-performance thin-layer chromatography, steroid hormones, chemometric treatment, principal component analysis.

Abstract

The opportunity of steroid hormone determination in urea samples of healthy donors and patients
with Cushing’s syndrome by thin-layer chromatography with densitometric detection has been
demonstrated. Chromatographic steroidal patterns processed by principal component analysis and soft
independent modeling of class analogy have been obtained.

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Published
2019-11-21
How to Cite
Obedkova, E. V., Kartsova, L. A., Kirsanov, D. O., & Golishev, A. A. (2019). Obtaining of characteristic profiles of steroid hormones by high-performance thin-layer chromatography. Sorbtsionnye I Khromatograficheskie Protsessy, 13(4). Retrieved from https://journals.vsu.ru/sorpchrom/article/view/1665