Ionic strength of the solution as the factor determining the mechanism of protein multicomponent ion-exchange sorption

  • Alexander T. Melenevsky research associate, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg, melenev@imc.macro.ru
  • Ekaterina N. Pavlova research associate, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg
  • Elena S. Nikiforova research associate, Institution of Russian Academy of Sciences Institute of Macromolecular Compounds Russian Academy of Sciences, St Petersburg
Keywords: Adsorption, Ion-exchangers, Proteins, Chromatography

Abstract

The investigation of ionic strength influence on protein mixture sorption (cytochrom c, lysozime,
ribonuclease) on cation exchangers was carried out. The possibility of transition from synergetic to
competitive sorption mechanism with ionic strength increasing was shown.

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References

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Published
2019-11-26
How to Cite
Melenevsky, A. T., Pavlova, E. N., & Nikiforova, E. S. (2019). Ionic strength of the solution as the factor determining the mechanism of protein multicomponent ion-exchange sorption. Sorbtsionnye I Khromatograficheskie Protsessy, 11(6). Retrieved from https://journals.vsu.ru/sorpchrom/article/view/1989